diff --git a/pkgs/development/python-modules/pyqt/4.x.nix b/pkgs/development/python-modules/pyqt/4.x.nix
index 2328894d2a30..5ffbd19228cf 100644
--- a/pkgs/development/python-modules/pyqt/4.x.nix
+++ b/pkgs/development/python-modules/pyqt/4.x.nix
@@ -14,6 +14,7 @@ in mkPythonDerivation {
   configurePhase = ''
     mkdir -p $out
     lndir ${dbus-python} $out
+    rm -rf "$out/nix-support"
 
     export PYTHONPATH=$PYTHONPATH:$out/lib/${python.libPrefix}/site-packages
 
diff --git a/pkgs/development/python-modules/pyqt/5.x.nix b/pkgs/development/python-modules/pyqt/5.x.nix
index 2b54308e3f02..3edf7e6e170b 100644
--- a/pkgs/development/python-modules/pyqt/5.x.nix
+++ b/pkgs/development/python-modules/pyqt/5.x.nix
@@ -32,6 +32,7 @@ in mkPythonDerivation {
 
     mkdir -p $out
     lndir ${dbus-python} $out
+    rm -rf "$out/nix-support"
 
     export PYTHONPATH=$PYTHONPATH:$out/lib/${python.libPrefix}/site-packages